COLLABORATIONS ON SKIN RESEARCH PROJECTS

Ever since our creation, Genoskin has collaborated with major international companies of the cosmetic, pharmaceutical or chemical sector to help science move forward and increase the range of reliable skin models available on the market. We strive to create innovative skin models with a high predictive value and for a wide range of applications. We are always open to new collaborations with public and private institutions to develop skin models that are adapted to your needs.

01. Research on skin metabolism

To contribute to fundamental research, Genoskin facilitates access to its models for academic laboratories. We have a particular interest in studying skin metabolism in all its aspects. Preferential rates apply for academic laboratories who would like to use our skin models to further their research projects. Should you like more information on our current range of human skin models and their applications, please visit our product pages. For a detailed quotation on our models and available research services, please don’t hesitate to contact us.

02. Research on pathological skin models

Should you be looking for a new pathological skin model for your research or study, we may also be able to help you.
If you have an interesting project in mind or simply require advice on ongoing skin research projects, please don’t hesitate to contact us. We look forward to hearing from you

03. Ongoing projects

Genoskin is involved in the Plasmaregen project supported by the French National Agency for Research. The project aims to study skin regeneration induced by cold atmospheric plasmas (CAPs) through controlled generation of reactive species.

Case study: The Plasmaregen Project

Description

Despite considerable progress, cutaneous wounds remain a major health concern. Skin response to injury follows a well-orchestrated succession of complex biological and molecular events to quickly achieve repair. Acute skin wounds heal with scarring but without regeneration. Recent research aims to elucidate homeostatic cues that may drive intrinsic regenerative pathways. However, recent research into the factors involved and the cellular and molecular response to injury have not yet elucidated the mechanisms that avoid scar formation. In addition, no substantial advances have been made in patient care, due to a lack in reliable therapies to treat pathological and chronic wounds.

Over the past few years, harnessing cold atmospheric plasmas (CAPs) for medical applications has turned into an innovative field of research, with diverse applications (such as decontamination and sterilization) based on the bactericidal activity of plasmas or for the treatment of tumors to inhibit metastasis and induce cancer cell death. More recently, CAP treatment was tested for the treatment of infected wounds, resulting in a reduction of the bacterial load and suggesting potential positive effects on wound healing. To date, human clinical trials have only enabled very few observations, with no supporting pre-clinical data and no understanding of the underlying mechanism of action of CAPs.

Plasmaregen objectives

improve CAP characterization and comparison in order to qualify predefined CAPs for wound healing applications
use novel electrochemical sensors and define a methodological approach to detect and measure reactive species produced in liquid media, cells and tissue after CAP exposure
investigate the biological effect (toxicity) and therapeutic effect (benefit) of plasma treatment at cell and tissue level and in animal models of skin wound healing.

Genoskin is involved in the latter two phases of the Plasmaregen project.

We welcome all innovative skin research projects.

Please don’t hesitate to contact us for more information.